Michael R Freeman Selected Research

Transitional Cell Carcinoma

3/2006	Behavioral profiling of human transitional cell carcinoma ex vivo.
9/2005	Trafficking of nuclear heparin-binding epidermal growth factor-like growth factor into an epidermal growth factor receptor-dependent autocrine loop in response to oxidative stress.
1/2003	A nuclear form of the heparin-binding epidermal growth factor-like growth factor precursor is a feature of aggressive transitional cell carcinoma.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Michael R Freeman Research Topics

Disease

76	Prostatic Neoplasms (Prostate Cancer) 12/2023 - 04/2002
61	Neoplasms (Cancer) 12/2023 - 04/2002
14	Neoplasm Metastasis (Metastasis) 01/2022 - 08/2007
9	Interstitial Cystitis (Interstitial Cystitis, Chronic) 01/2015 - 08/2007
7	Urinary Bladder Neoplasms (Bladder Cancer) 08/2015 - 01/2003
6	Adenocarcinoma 10/2023 - 01/2012
6	Hypercholesterolemia 09/2012 - 07/2006
6	Carcinoma (Carcinomatosis) 08/2012 - 12/2002
5	Breast Neoplasms (Breast Cancer) 01/2019 - 06/2003
5	Disease Progression 11/2018 - 01/2003
4	Inflammation (Inflammations) 11/2023 - 07/2008
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020 - 10/2003
3	Circulating Neoplastic Cells 01/2019 - 01/2016
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 10/2010 - 01/2003
3	Hyperplasia 09/2010 - 05/2002
3	Transitional Cell Carcinoma 03/2006 - 01/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2012
2	Acute Coronary Syndrome 01/2020 - 01/2019
2	Atherosclerosis 01/2020 - 06/2007
2	Pain (Aches) 01/2015 - 01/2012
2	Carcinogenesis 01/2012 - 10/2007
2	Hypertrophy 12/2006 - 05/2002

Drug/Important Bio-Agent (IBA)

30	CholesterolIBA 01/2023 - 04/2002
26	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2002
19	Androgen Receptors (Androgen Receptor)IBA 12/2023 - 12/2002
14	LipidsIBA 01/2020 - 04/2002
13	AndrogensIBA 11/2023 - 12/2002
11	Biomarkers (Surrogate Marker)IBA 06/2020 - 06/2003
8	ErbB Receptors (EGF Receptor)IBA 01/2020 - 11/2004
7	Transcription Factors (Transcription Factor)IBA 10/2023 - 01/2013
7	Phosphotransferases (Kinase)IBA 01/2022 - 11/2004
7	Messenger RNA (mRNA)IBA 01/2020 - 12/2002
7	Hormones (Hormone)IBA 01/2018 - 01/2004
7	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2014 - 12/2002
5	RNA (Ribonucleic Acid)IBA 12/2023 - 11/2012
5	Ezetimibe (Zetia)FDA Link 01/2022 - 03/2009
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2018 - 06/2006
5	Caveolin 1IBA 09/2013 - 08/2007
5	Epidermal Growth Factor (EGF)IBA 02/2009 - 04/2002
4	Peptides (Polypeptides)IBA 01/2020 - 12/2002
4	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 06/2011 - 04/2002
4	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 02/2009 - 04/2005
4	Heparin (Liquaemin)FDA LinkGeneric 02/2009 - 12/2002
3	DNA (Deoxyribonucleic Acid)IBA 06/2023 - 05/2002
3	Glutamine (L-Glutamine)FDA Link 01/2023 - 12/2011
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 01/2013
3	EnzymesIBA 01/2023 - 01/2012
3	27-hydroxycholesterolIBA 01/2023 - 01/2017
3	Prostate-Specific Antigen (Semenogelase)IBA 01/2021 - 04/2004
3	LigandsIBA 12/2016 - 10/2007
3	ElementsIBA 01/2013 - 04/2004
3	SialoglycoproteinsIBA 01/2012 - 08/2007
3	Tyrosine (L-Tyrosine)FDA Link 07/2009 - 04/2005
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2008 - 09/2005
2	enzalutamideIBA 12/2023 - 01/2016
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 03/2021
2	olaparibIBA 01/2022 - 01/2021
2	CytokinesIBA 01/2021 - 02/2004
2	Phenobarbital (Luminal)FDA Link 01/2021 - 01/2016
2	AutoantigensIBA 01/2020 - 01/2019
2	Keratin-8 (Keratin 8)IBA 01/2019 - 06/2003
2	ForminsIBA 11/2018 - 07/2009
2	LDL Receptors (LDL Receptor)IBA 01/2017 - 01/2017
2	Ubiquitin-Specific ProteasesIBA 08/2015 - 03/2012
2	Deubiquitinating EnzymesIBA 08/2015 - 03/2012
2	Amino Acids FDA Link 05/2015 - 06/2011
2	Small Interfering RNA (siRNA)IBA 09/2013 - 09/2010
2	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2013 - 08/2007
2	Metalloproteases (Metalloproteinases)IBA 11/2012 - 09/2005
2	GlycopeptidesIBA 12/2011 - 01/2011
2	CalciumIBA 09/2010 - 12/2002
2	p38 Mitogen-Activated Protein KinasesIBA 02/2009 - 06/2007
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 07/2008 - 09/2005
2	Interleukin-6 (Interleukin 6)IBA 02/2007 - 02/2004
2	MitogensIBA 12/2006 - 12/2002
2	NF-kappa B (NF-kB)IBA 11/2006 - 04/2004
2	CaveolinsIBA 02/2004 - 04/2002
1	CarbohydratesIBA 12/2023
1	Blood Glucose (Blood Sugar)IBA 12/2023
1	Insulin-Like Growth Factor I (IGF-1)IBA 12/2023
1	Insulin (Novolin)FDA Link 12/2023
1	Sucrose (Saccharose)IBA 12/2023
1	Arginine (L-Arginine)FDA Link 06/2023
1	3' Untranslated Regions (3' UTR)IBA 01/2023
1	Pyrimidine NucleotidesIBA 01/2023
1	Competitive Endogenous RNAIBA 01/2023
1	HexosaminesIBA 01/2023
1	purineIBA 01/2023
1	Glutathione (Reduced Glutathione)IBA 01/2023
1	GlutaminaseIBA 01/2023
1	Essential Amino AcidsIBA 01/2023
1	Protein Kinases (Protein Kinase)IBA 01/2022
1	MAP Kinase Kinase 7IBA 01/2022

Therapy/Procedure

20	Therapeutics 12/2023 - 11/2004
13	Castration 01/2023 - 12/2011
2	Prostatectomy (Retropubic Prostatectomy) 01/2022 - 01/2020
2	Drug Therapy (Chemotherapy) 07/2015 - 03/2012
2	Intravesical Administration 07/2008 - 03/2006
1	Immunotherapy 12/2023
1	Carbohydrate-Restricted Diet (Low Carbohydrate Diet) 12/2023